Seminars & Events

Friday, October 4, 2013: Dr. Laurie Ryan, SMCM '86 (National Institute on Aging) will speak on "Alzheimer's Disease: Targets and Treatments" at 3:00 pm in Goodpaster Hall 195.

Monday, October 21, 2013: Dr. Greg Elmer (University of Maryland Baltimore) will speak on "Domains and Constructs in Motivation: Where Does the Habenula Fit In?" at 4:45 pm in Goodpaster Hall 195

Friday, October 25, 2013:  Dr. Terry Davidson (American University) will speak on "Why We Overeat and Become Obese?  It Could be What We Think!" at 3:00 pm in Goodpaster Hall 195.

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Alumni Highlight

Dr. Gwen Calhoon '06 recently received her Ph.D. in Neuroscience from the University of Maryland Baltimore, and was inducted into Nu Rho Psi.

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SMP Spotlight

Katie Gluskin and Jeff Haus present their SMP
Katie Gluskin and Jeff Haus, "Entorhinal Cortex Lesions, Habituation, and Latent Inhibition," 2013. Gluskin and Haus, the 2013 co-winners of the Neuroscience Award, infused a neurotoxin into the entorhinal cortex of rats to induce a lesion, and measured the resulting habituation and latent inhibition behavior within a fear conditioning paradigm.

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Dippel, W. Chris (2012).  Cognitive and behavioral impairments evaluated in the neonatal ventral hippocampus lesion rat model of schizophrenia. (Mentor: A.M. Brady)

Abstract 

The neonatal ventral hippocampus lesion (NVHL) is a proposed rat model for schizophrenia. The present study assessed the effects of the NVHL in social interaction, pre-pulse inhibition, spontaneous locomotion, response to amphetamine, set-shifting, and reversal learning. Rats with an NVHL showed deficits in pre-pulse inhibition, and set-shifting as well as a stronger response to amphetamine. Few effects were found in social interaction, and there was no effect during reversal learning. Pre-exposed rats made more perseverative errors during the set-shift task suggesting the NVHL causes impairments in PFC functioning. Percent pre-pulse inhibition was negatively correlated with trials to criterion on the shift day of the set-shifting task, response to amphetamine, and spontaneous locomotion suggesting there may be a relationship between behavior deficits elicited by the NVHL.