Seminars & Events
Thursday, September 11, 2014: Dr. Bevil Conway (Wellesley College) will speak on his research in visual neuroscience and color at 4:30 pm in Goodpaster Hall 195.
Monday, October 27, 2014: Dr. Todd Gould (University of Maryland Baltimore) will speak on "Genes to behaviors to treatments in bipolar disorder" at 4:45 pm in Goodpaster Hall 195.Friday, December 5, 2014: Dr. Brian Mathur (University of Maryland Baltimore) will speak on "Braking bad: Aberrant inhibitory neurotransmission in addiction" at 3:00 pm in Goodpaster Hall 195.
Burke, Jesse (2012). Effects of adolescent exposure to olanzapine on adulthood rodents. (Mentor: A. Bailey)
With greater understanding of certain mental illnesses, there comes the ability to identify and start treatment at an earlier age. Starting medication is one line of defense when a mental illness is identified, and when that illness is identified in adolescence this process is no different. The complication arises when introduction of these drugs occurs during adolescence, a period when the nervous system is rapidly changing. Studying the long-term effects of starting medications at an early age is critical for understanding if the treatment of symptoms outweighs the potential behavioral/neurobiological consequences in adulthood. In the current study, we administered olanzapine (OLA), a common atypical antipsychotic that is prescribed for schizophrenia, bipolar disorder, and autism to adolescent rats to see how this affected conditioned reinforcement through a Pavlovian reinforcer devaluation task in adulthood. We also wanted to see if adolescent OLA treatment affected fear and appetitive extinction tasks in adulthood. We did not find any significant impairment between vehicle and OLA treated rodents in conditioned reinforcement or appetitive extinction, although some interesting behavioral trends were noted.