Seminars & Events
Thursday, September 11, 2014: Dr. Bevil Conway (Wellesley College) will speak on his research in visual neuroscience and color at 4:30 pm in Goodpaster Hall 195.
Monday, October 27, 2014: Dr. Todd Gould (University of Maryland Baltimore) will speak on "Genes to behaviors to treatments in bipolar disorder" at 4:45 pm in Goodpaster Hall 195.Friday, December 5, 2014: Dr. Brian Mathur (University of Maryland Baltimore) will speak on "Braking bad: Aberrant inhibitory neurotransmission in addiction" at 3:00 pm in Goodpaster Hall 195.
Reid, Chelsea (2007). Periadolescents on Methamphetamine: The Impact of an Escalating Dose Regimen of Methamphetamine on Non-Spatial Working Memory and Serotonin within the Hippocampus. Winner of a Sigma Xi Grant-in-Aid of Research.
Dr. Anne Marie Brady
The use of methamphetamine (METH) worldwide, in adults and adolescents, has led to increased research on the neurotoxicity to brain regions and the cognitive deficits caused by METH. The current experiment focused on the effects of METH on hippocampus dependent non-spatial and spatial working memory and hippocampal serotonin levels with an escalating dose model of METH use in periadolescent rats. Using 18 male Spraque-Dawley rats, the novel object recognition task and the discrete paired-trials delayed alternation task measured working memory and optical density quantified serotonin found in the hippocampus. The effects on working memory and hippocampal serotonin were found to be non-significant. Further research should utilize the escalating dose model to determine the developmental issues caused by periadolescent METH use.