Seminars & Events
Thursday, September 11, 2014: Dr. Bevil Conway (Wellesley College) will speak on his research in visual neuroscience and color at 4:30 pm in Goodpaster Hall 195.
Monday, October 27, 2014: Dr. Todd Gould (University of Maryland Baltimore) will speak on "Genes to behaviors to treatments in bipolar disorder" at 4:45 pm in Goodpaster Hall 195.Friday, December 5, 2014: Dr. Brian Mathur (University of Maryland Baltimore) will speak on "Braking bad: Aberrant inhibitory neurotransmission in addiction" at 3:00 pm in Goodpaster Hall 195.
Medley, Vanessa (2008). Examining Behavioral Flexibility in Long-Evans Rats Following Lesions to the Prefrontal Cortex. Mentor: Dr. Aileen Bailey
The current study evaluated the effects of lesions to the prefrontal cortex (PFC) on learning set acquisition and formation in a visually-cued water maze (MWM) task and olfactory discrimination reversal (ODR) task. The subjects were also tested in an open field apparatus and in novel object recognition (NOR) to ensure that surgical procedures did not affect their general functioning or working memory, respectively. We hypothesized that learning set formation would be inhibited or blocked by the PFC lesion but general functioning and working memory would remain intact. The results indicated that the control subjects were able to form a learning set in the ODR task and perform significantly above chance. The PFC lesioned rats did not form a learning set in the ODR task and performed below chance. There were no group differences in the MWM task suggesting that visual cues are not sufficient in learning set formation or methods should be altered. All of the animals exhibited no change in activity levels or working memory.