Seminars & Events
Thursday, September 11, 2014: Dr. Bevil Conway (Wellesley College) will speak on his research in visual neuroscience and color at 4:30 pm in Goodpaster Hall 195.
Monday, October 27, 2014: Dr. Todd Gould (University of Maryland Baltimore) will speak on "Genes to behaviors to treatments in bipolar disorder" at 4:45 pm in Goodpaster Hall 195.Friday, December 5, 2014: Dr. Brian Mathur (University of Maryland Baltimore) will speak on "Braking bad: Aberrant inhibitory neurotransmission in addiction" at 3:00 pm in Goodpaster Hall 195.
McGill, Jacquelyn (2007). The Effects of Diazepam on Anxiety with Repeated Testing in Rats. Winner of a Sigma Xi Grant-in-Aid of Research and a Psi Chi Undergraduate Research Grant.
Dr. Anne Marie Brady
The locus coeruleus (LC) and the amygdala are two areas of the brain involved in anxiety. Benzodiazepines, such as diazepam, decrease anxiety behaviorally. Histological data using cFos also supports diazepam’s role in reducing anxiety, through possible regulation by the LC and amygdala. It was hypothesized that a dose-dependent decrease in anxiety after administration of 0, 0.5 and 1.0 mg/kg of diazepam would be seen both on the elevated plus maze and open field after repeated testing and on anxiety-induced cFos expression in both the LC and amygdala. No significant effects of dose were seen behaviorally or in the number of activated cells, suggesting either these areas do not influence anxiety or that different experiments are needed to see their effects.