Seminars & Events
Thursday, September 11, 2014: Dr. Bevil Conway (Wellesley College) will speak on his research in visual neuroscience and color at 4:30 pm in Goodpaster Hall 195.
Monday, October 27, 2014: Dr. Todd Gould (University of Maryland Baltimore) will speak on "Genes to behaviors to treatments in bipolar disorder" at 4:45 pm in Goodpaster Hall 195.Friday, December 5, 2014: Dr. Brian Mathur (University of Maryland Baltimore) will speak on "Braking bad: Aberrant inhibitory neurotransmission in addiction" at 3:00 pm in Goodpaster Hall 195.
Callahan, Lauren (2006). The Effects Of Isolation Rearing In Adolescence On Behavioral Sensitization To Methamphetamine In Adulthood.
Mentor: Dr. Anne Marie Brady
Environmental stress has been shown to play a significant role in addictive behavior in both animal models and in humans. The present study investigates whether the stress of social isolation in adolescence increases measures of behavioral sensitization to methamphetamine in adult rats. Male Sprague-Dawley rats were reared either in isolation (n=11) or housed two to a cage (n=12) beginning in adolescence. At the onset of adulthood, rats were randomly assigned to receive either methamphetamine (n=15) or saline (n=8), and locomotor activity was measured in activity chambers at baseline, over five chronic days, and at a later test day. Results reveal that rats reared in isolation in adolescence do not exhibit higher levels of sensitization to methamphetamine than non-isolated rats. In conclusion, the current study does not show that isolation rearing increases sensitization to methamphetamine.
Read the paper (pdf format,260KB)