Seminars & Events

Thursday, September 11, 2014: Dr. Bevil Conway (Wellesley College) will speak on his research in visual neuroscience and color at 4:30 pm in Goodpaster Hall 195.

Monday, October 27, 2014: Dr. Todd Gould (University of Maryland Baltimore) will speak on "Genes to behaviors to treatments in bipolar disorder" at 4:45 pm in Goodpaster Hall 195

Friday, December 5, 2014:  Dr. Brian Mathur (University of Maryland Baltimore) will speak on "Braking bad: Aberrant inhibitory neurotransmission in addiction" at 3:00 pm in Goodpaster Hall 195.

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Alumni Highlight

Check out Jordan Gaines Lewis '11's award-winning blog, Gaines on Brains. 

gainesonbrains.com

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SMP Spotlight

Katie Gluskin and Jeff Haus present their SMP
Katie Gluskin and Jeff Haus, "Entorhinal Cortex Lesions, Habituation, and Latent Inhibition," 2013. Gluskin and Haus, the 2013 co-winners of the Neuroscience Award, infused a neurotoxin into the entorhinal cortex of rats to induce a lesion, and measured the resulting habituation and latent inhibition behavior within a fear conditioning paradigm.

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Lubben, Jade (2006).  Exercise As A Protective Mechanism Against Chronic Stress Induced Memory Impairments And Hippocampal Damage In Rats.
Mentor: Dr. Anne Marie Brady

Abstract

Chronic stress and release of the stress hormones glucocorticoids (GC’s) can cause learning and memory impairments.  Chronic binding of GC’s is toxic to neurons of the hippocampus, the area of the brain involved in learning and memory.  The expression of brain-derived neurotrophic factor (BDNF) is also suppressed in times of chronic stress.  The decrease in BDNF, a protein that supports the functional integrity of neurons, may be the key factor underlying stress-induced memory impairments.  Voluntary exercise by humans and rodents appears to enhance memory and increase the expression of hippocampal BDNF. The current study investigated whether 2 weeks of voluntary exercise by rats would protect against memory impairments caused by co-occurring restraint stress (1 hour per day). After 2 weeks of the stress condition, exercise condition, stress and exercise condition, or control condition, the animals’ non-spatial hippocampus-dependent memory was tested using the novel object recognition task. Results showed only a positive main effect of exercise on memory, consistent with previous research.  Contrary to the hypothesis, stress had no effect.  Limitations of the study and suggestions for future research are discussed.

Read the paper (pdf format, 245KB)