Seminars & Events
Friday, October 4, 2013: Dr. Laurie Ryan, SMCM '86 (National Institute on Aging) will speak on "Alzheimer's Disease: Targets and Treatments" at 3:00 pm in Goodpaster Hall 195.
Monday, October 21, 2013: Dr. Greg Elmer (University of Maryland Baltimore) will speak on "Domains and Constructs in Motivation: Where Does the Habenula Fit In?" at 4:45 pm in Goodpaster Hall 195.
Friday, October 25, 2013: Dr. Terry Davidson (American University) will speak on "Why We Overeat and Become Obese? It Could be What We Think!" at 3:00 pm in Goodpaster Hall 195.
Dr. Gwen Calhoon '06 recently received her Ph.D. in Neuroscience from the University of Maryland Baltimore, and was inducted into Nu Rho Psi.
Holmes, Ashley (2011). Effects of orexin A in the nucleus basalis magnocellularis (nBM) on olfactory discrimination acquisition and reversal. (Mentor: A. Bailey)
The orexins or hypocretins are a family of neuropeptides found in a variety of different brain structures. The orexins produce excitatory effects and can be split into two types, orexin A (OxA) and orexin B (OxB). The orexins originate in the lateral hypothalamus but project to various other areas of the brain. Orexin interactions with the basal forebrain cholinergic system (BFCS) in particular are hypothesized to be related to arousal and attention and the BFCS is seen to be responsible for normal attentional functioning. Previous research shows that OxA plays an important role in the BFCS attention system. Therefore, we looked at the effects of OxA in an olfactory discrimination acquisition and reversal task. Results supported the hypothesis that orexin A infusions in the nBM did significantly increase attention on olfactory discrimination acquisition and reversal. Therefore, in general, rats who received OxA infusions did have an increase in attention when compared to rats given aCSF infusions.