Seminars & Events

Friday, October 4, 2013: Dr. Laurie Ryan, SMCM '86 (National Institute on Aging) will speak on "Alzheimer's Disease: Targets and Treatments" at 3:00 pm in Goodpaster Hall 195.

Monday, October 21, 2013: Dr. Greg Elmer (University of Maryland Baltimore) will speak on "Domains and Constructs in Motivation: Where Does the Habenula Fit In?" at 4:45 pm in Goodpaster Hall 195

Friday, October 25, 2013:  Dr. Terry Davidson (American University) will speak on "Why We Overeat and Become Obese?  It Could be What We Think!" at 3:00 pm in Goodpaster Hall 195.

+ VIEW CALENDAR

Alumni Highlight

Dr. Gwen Calhoon '06 recently received her Ph.D. in Neuroscience from the University of Maryland Baltimore, and was inducted into Nu Rho Psi.

+ MORE

 

   

 

 

 

SMP Spotlight

Katie Gluskin and Jeff Haus present their SMP
Katie Gluskin and Jeff Haus, "Entorhinal Cortex Lesions, Habituation, and Latent Inhibition," 2013. Gluskin and Haus, the 2013 co-winners of the Neuroscience Award, infused a neurotoxin into the entorhinal cortex of rats to induce a lesion, and measured the resulting habituation and latent inhibition behavior within a fear conditioning paradigm.

+ MORE

Gibbons, Kaitlin (2010).   Pressure mechanosensory neuron interactions and connections in the leeches Hirudo verbana and Macrobdella decora.   Mentor: Dr. Michael Baltzley

Abstract 

The European medicinal leech Hirudo verbana has four mechanosensory pressure neurons (P cells) in each midbody ganglion. Within an isolated ganglion, P cells have complex mutually inhibitory connections. When one P cell is stimulated intracellularly, the other P cells have a weak depolarization followed by a strong hyperpolarization. This complex response appears to be mediated by a combination of electrical coupling, monosynaptic excitation and polysynaptic inhibition. I examined the P cell homologues in the American medicinal leech Macrobdella decora. I found that intracellular stimulation of one P cell causes a slight depolarization in the other P cells. Experiments performed in a high Mg2+, 0 Ca2+ saline and a high Mg2+, high Ca2+ saline suggest that the P cells in M. decora have an electrical coupling, a monosynaptic excitation and polysynaptic inhibition, similar to the connections between P cells in H. verbana. Therefore, the difference in net response between these two species seems to be based on differences in the strengths of the electrical and chemical connections. I also tested the connections between P cells in both M. decora and H. verbana in normal leech saline with bicuculline, a GABA-antagonist. Our preliminary results show that the polysynaptic inhibition was eliminated in both species, suggesting that the inhibition is due to GABA-mediated Cl- channels.