Seminars & Events

Thursday, September 11, 2014: Dr. Bevil Conway (Wellesley College) will speak on his research in visual neuroscience and color at 4:30 pm in Goodpaster Hall 195.

Monday, October 27, 2014: Dr. Todd Gould (University of Maryland Baltimore) will speak on "Genes to behaviors to treatments in bipolar disorder" at 4:45 pm in Goodpaster Hall 195

Friday, December 5, 2014:  Dr. Brian Mathur (University of Maryland Baltimore) will speak on "Braking bad: Aberrant inhibitory neurotransmission in addiction" at 3:00 pm in Goodpaster Hall 195.


Alumni Highlight

Check out Jordan Gaines Lewis '11's award-winning blog, Gaines on Brains.




SMP Spotlight

Katie Gluskin and Jeff Haus present their SMP
Katie Gluskin and Jeff Haus, "Entorhinal Cortex Lesions, Habituation, and Latent Inhibition," 2013. Gluskin and Haus, the 2013 co-winners of the Neuroscience Award, infused a neurotoxin into the entorhinal cortex of rats to induce a lesion, and measured the resulting habituation and latent inhibition behavior within a fear conditioning paradigm.


Bailey, A. M., Kallarackal, A. J., Chen, M. , & Simard, J. M. (2006, October). Apamin significantly improves spatial cognition in a mouse model of Neurofibromatosis 1. Poster session to be presented at the Society for Neuroscience Annual Meeting, Atlanta, GA.


Neurofibromatosis 1 (NF1) is a common genetic disorder known to cause a variety of physiological symptoms and is associated with visuospatial learning impairments.  Investigations with a mouse model of neurofibromatosis 1 (Nf1) have previously found impaired long-term potentiation, a significant up-regulation of small conductance calcium activated potassium type 1 (SK1) channels, and impaired spatial learning in a water maze.  We investigated possible involvement of SK1 channels in spatial learning deficits in Nf1+/- mice by administering apamin, a potent SK channel blocker, and examining performance in a water maze.  Forty-four Nf1+/- mice and 41 C57BL6 (wild type, WT) mice were administered either 0.2 mg/kg apamin, 0.4 mg/kg apamin, or physiological saline through i.p. injection or micro-osmotic pumps.  All mice were given 24 spatial training trials over 6 days with probe tests conducted immediately following the 4th, 12th, 20th, and 24th trials. Immediately following the final probe test, mice were given a visual test in the water maze. There were no differences between Nf1+/- and WT mice in the visual test.  Nf1+/- mice treated with saline were significantly impaired in the water maze in comparison to WT mice.  Both 0.2 mg/kg and 0.4 mg/kg of apamin significantly improved water maze performance in the Nf1+/- mice on the third day of training and on the corresponding probe test.  The results indicate a significant improvement in spatial cognition following apamin treatment in Nf1+/- mice and a potential direction for future research regarding the learning deficits seen in NF1.